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Fig. 2 | Cell & Bioscience

Fig. 2

From: RBX1 regulates PKM alternative splicing to facilitate anaplastic thyroid carcinoma metastasis and aerobic glycolysis by destroying the SMAR1/HDAC6 complex

Fig. 2

RBX1 facilitated the proliferation and migration of ATC cells. A Western blotting was performed to identify the RBX1 expression levels in CAL62 and KMH-5M cells stably transfected with shRBX1 plasmid. B RBX1 expression levels in the 8305C cells stably transfected with HA-RBX1 plasmid were measured using a western blot. C Transwell assays of CAL62 cells transfected with shRBX1 plasmid. **P < 0.01. D Transwell assays of 8305C cells transfected with HA-RBX1 plasmid. **P < 0.01. E EdU assays of CAL62 cells transfected with shRBX1 plasmid. **P < 0.01. F EdU assays of 8305C cells transfected with HA-RBX1 plasmid. **P < 0.01. G, H H&E staining of the sections of metastatic nodules in the lungs embedded with paraffin. *P < 0.05, **P < 0.01

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Cell & Bioscience

ISSN: 2045-3701

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