Fig. 1

RBX1 is overexpressed in ATC and closely correlated with poor prognosis in patients. A, B RBX1 mRNA expression levels in the ATC tissues together with the normal tissues adjacent to the tumor were investigated by qRT-PCR. **P < 0.01. C, D Expression levels of RBX1 protein in ATC tissues and the normal tissues adjacent to the tumor were investigated by western blotting. **P < 0.01. E RBX1 protein expression in the ATC tissues and the normal tissues adjacent to the tumor were determined using immunohistochemistry. Scale bar, 50 μm. F, G RBX1 protein and mRNA levels in ATC and PTC cell lines. ***P < 0.001. H Kaplan–Meier curves were used to visualize the overall survival of both low and high RBX1 expression of ATC patients. ***P < 0.001