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Table 2 Clinicopathological characteristics of 434 patients with PCa from TCGA database

From: ARPC1A correlates with poor prognosis in prostate cancer and is up-regulated by glutamine metabolism to promote tumor cell migration, invasion and cytoskeletal changes

  

ARPC1A expression

 

Variables

N

Low

High

P value

Total, n (%)

434

185 (42.6)

249 (57.4)

 

Age, n (%)

   

0.336

  < 60 years

178 (41.0)

71 (38.4)

107 (43.0)

 

  ≥ 60 years

256 (59.0)

114 (61.6)

142 (57.0)

 

T Stage, n (%)

   

 < 0.001*

 T2

157 (36.2)

104 (56.2)

53 (21.3)

 

 T3

256 (59.0)

76 (41.1)

180 (72.3)

 

 T4

21 (4.8)

5 (2.7)

16 (6.4)

 

N Stage, n (%)

   

0.007*

 N0

291 (67.1)

137 (74.1)

154 (61.8)

 

 N1

143 (32.9)

48 (25.9)

95 (38.2)

 

M Stage, n (%)

   

0.763

 M0

404 (93.1)

173 (93.5)

231 (92.8)

 

 M1

30 (6.9)

12 (6.5)

18 (7.2)

 

Gleason Score, n (%)

   

0.094

  ≤ 6

25 (5.8)

14 (7.6)

11 (4.4)

 

 7

91 (21.0)

45 (24.3)

46 (18.5)

 

  ≥ 8

301 (73.2)

126 (68.1)

192 (77.1)

 

Race, n (%)

   

0.346

 White

359 (82.7)

159 (86.0)

200 (80.4)

 

 Yellow

26 (6.0)

11 (5.9)

15 (6.0)

 

 Black

7 (1.6)

2 (1.1)

5 (2.0)

 

 Unknown

42 (9.7)

13 (7.0)

29 (11.6)

 

Adjuvant therapy, n (%)

   

0.283

 Yes

155 (35.7)

62 (33.5)

93 (37.3)

 

 No

103 (23.7)

40 (21.6)

63 (25.4)

 

 Unknown

176 (40.6)

83 (44.9)

93 (37.3)

 
  1. *P < 0.05