Fig. 6

Knockdown of ARPC1A inhibits cytoskeleton formation, but has no impact on cell cycle progression and cell proliferation. A–H Differences in cell cycle stage between control and ARPC1A siRNA-transfected PCa cells, as determined by flow cytometry analysis. *: P < 0.05; ns: no statistical significance. I–J Differences in cell proliferation between control and ARPC1A siRNA-transfected PCa cells, as determined using a CCK-8 assay. *: P < 0.05; ns: no statistical significance. K Immunofluorescence analysis of the actin cytoskeleton and cellular morphology in control and ARPC1A siRNA-transfected PC-3 cells. DAPI 4’,6-diamidino-2-phenylindole, FITC fluorescein isothiocyanate