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Table 2 GLIS3, NKX2.2, PAX8, and FOXE1 to nearby genes (within 5 kb regions of TSS) in rat thyroid follicular PCCl3 cells

From: GLIS3 regulates transcription of thyroid hormone biosynthetic genes in coordination with other thyroid transcription factors

Category

geneSYM

rGLIS3 target

rNKX2.1 target

rPAX8 target

rFOXE1 target

TH synthesis

Slc5a5

+

+

+

+

Slc26a4

+

+

+

Tpo

+

Tshr

+

+

+

Iyd

Slc16a2

+

+

+

Duox1

+

Duoxa1

+

+

Duox2

+

+

+

+

Tg

+

Duoxa2

+

+

+

+

TSH induced

Adm2

+

+

+

Sod3

+

+

+

+

Cdh13

+

Dio1

+

+

+

Cdh16

+

+

+

+

Pde4d

+

+

+

+

Ano1

+

+

+

Kcnq1

Thyroid function

Txnrd1

+

+

+

+

Txnrd2

+

+

+

Gnas

+

+

+

Fam20c

+

+

+

+

Clcn5

Dio2

Gnaq

+

+

+

Gpx1

+

+

+

Kcne2

Txn1

+

+

+

Txn2

+

+

+

Thyroid TFs

Glis3

Hhex

+

+

+

+

Pax8

+

+

+

+

Nkx2-1

+

+

+

+

Foxe1

+

+

+

+