Fig. 7From: GLIS3 regulates transcription of thyroid hormone biosynthetic genes in coordination with other thyroid transcription factorsSchematic view of GLIS3 regulation in the expression of target genes with other TFs. GLIS3 does not affect PAX8 or NKX2.1 binding nor the open/closed chromatin structure at their regulatory regions of several GLIS3 target genes but may promote transcriptional activation by enhancing the interaction of regulatory regions with Pol II complexesBack to article page