Fig. 2
From: Metabolic reprogramming in colorectal cancer: regulatory networks and therapy
Amino Acid Metabolism in Cancer Cells and Its Crosstalk with Other Signal Pathways. Exogenous and endogenous amino acids are metabolized in CRC cells to fuel the unique biosynthetic and energetic requirements of the tumor, and metabolic enzymes involved in amino acid metabolism are regulated y different signals. Brown boxes indicate metabolic enzymes. Blue boxes represent factors that alter amino acid metabolism