Skip to main content

Table 1 List of the DEGs and DEPs common to all CFTR mutations

From: Mutation-class dependent signatures outweigh disease-associated processes in cystic fibrosis cells

 

G542X

F508del

N1303K

G551D

I1234V

Genes

Log2 FC

ARHGAP45

− 0.47

− 0.67

− 0.45

− 0.70

1.10

ATP5D

− 0.47

-0.43

− 0.53

− 0.64

0.53

HERC5

1.30

0.64

1.10

1.18

0.74

IFI44

2.90

1.53

2.20

2.67

1.47

IFIT1

1.34

0.69

1.19

1.35

0.71

ISG15

1.96

0.83

1.46

1.65

0.82

NIBAN1

1.15

− 1.29

0.82

− 1.66

− 5.54

TMEM259

− 0.50

− 0.57

− 0.59

− 0.62

0.77

TMX4

− 1.90

− 2.87

− 2.64

− 4.58

− 1.05

ZFP28

− 6.64

− 5.91

− 2.21

− 5.59

− 6.09

Proteins

Log2 FC

BACH

0.19

0.77

0.44

0.39

− 0.24

ERO1A

0.22

0.59

0.46

0.21

0.23

ESYT1

0.26

0.37

0.24

0.14

0.60

FINC

0.57

0.63

0.24

− 0.60

0.74

GARS

− 0.17

− 0.26

− 0.27

− 0.19

− 0.31

RAN

-0.39

− 0.70

− 0.59

− 0.34

− 0.22

RPN1

0.22

0.33

0.16

0.29

0.38

SERPH

− 0.37

− 0.76

− 0.45

− 0.21

0.60

UBP14

0.21

− 0.16

− 0.33

0.40

0.42

VPS35

0.31

0.16

0.15

0.15

0.37

  1. Data are expressed as Log2 fold change (FC) in mutant cells versus WT cell line. The orange font represents upregulated genes or proteins while blue font represents downregulated genes or proteins. The values shown here were obtained from RNA-Seq and MS analysis
Back to article page

Cell & Bioscience

ISSN: 2045-3701

Contact us