Fig. 8
From: Mutation-class dependent signatures outweigh disease-associated processes in cystic fibrosis cells
Integration and correlation of transcriptomics and proteomics data sets A Integration of transcriptomic and proteomic data showed that ~ 810 proteins in the proteomics dataset have a match in the transcriptomics dataset. Results are represented in a Venn diagram. B–F Left panels: percentage of differentially expressed (DE) and not DE genes/proteins for each CFTR mutant cell line; Middle panels: Among the DE genes/proteins some were only differentially expressed in the transcriptomics dataset (RNA), others in the proteomics dataset (Protein), and others in both datasets (RNA & Protein); Right panels: correlation between RNA and protein expression levels of the gene/proteins significant in both datasets (RNA & Protein, so-called gene/protein pairs) in the different mutant CFTR cell lines