Fig. 6
From: Mutation-class dependent signatures outweigh disease-associated processes in cystic fibrosis cells
Gene Ontology (GO) enrichment analysis for the DEPs associated with CFTR mutations For each mutation, the size of the dotted squared is proportional to the ratio between the total number of enriched GO terms and the number of DEPs, reflecting the strength of the functional signature in the protein set. Inside each square, the enriched GO terms are summarized by donut charts for each of the three branches of the GO tree—biological process (in green), cellular component (in blue) and molecular function (in orange). The size of each chart is directly proportional to the number of significant GO terms assigned to the corresponding branch (no chart is displayed if no significant terms were found). Donut charts show the number of enriched GO terms grouped by functional categories, according to the selected representative identifier (see main text). Categories are plotted clockwise in the donut chart from the highest to lowest number of significant GO terms, with the category identifiers presented by the chart in the same order