Fig. 8

L. acidophilus supplementation recovered bacterial phenylalanine metabolism of ALD mice. A Shannon and chao indexes measured the alpha diversities of intestinal bacteria of ALD mice with and without L. acidophilus supplementation. B PLS-DA revealed the beta diversity of intestinal bacteria. C Significantly different bacterial taxa examined by LEfSe analysis between ALD mice with and without L. acidophilus supplementation. Alcohol exposed and control groups. D KEEG module abundances of amino acid metabolism that predicted by PICRUSt between ALD mice with and without L. acidophilus supplementation. E Comparison of the abundances of phenylalanine metabolizing enzymes D-lactate dehydrogenase and phenylacetaldehyde dehydrogenase between ALD mice with and without L. acidophilus supplementation. *p value < 0.05