Fig. 2

Phenylalanine metabolism was destroyed in alcohol administration mice. A Comparison of KEEG module abundances of amino acid metabolism that predicted by PICRUSt using 16S data between alcohol exposed and control groups. B Comparison of the abundance of phenylalanine and its’ metabolites phenylpyruvate and 3-phenyllactic acid in Chronic-binge ethanol feeding mice and control mice. C Comparison of the ratios of phenylpyruvate to phenylalanine and 3-Phenyllactic acid to phenylalanine between the above groups. D The pathway of phenylalanine catabolism by gut microbes (refered to Martin F. Laursen et al. [27] and Dylan Dodd et al. [28]). E Abundances of Bacterial phenylalanine metabolizing enzymes D-lactate dehydrogenase and phenylacetaldehyde dehydrogenase predicted by PICRUSt method in the above groups. n.s, no significant. *p value < 0.05. **p value < 0.01