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Fig. 4 | Cell & Bioscience

Fig. 4

From: Dynamic single-cell RNA-seq analysis reveals distinct tumor program associated with microenvironmental remodeling and drug sensitivity in multiple myeloma

Fig. 4

Differential expression analysis of tumor cells with different immune reactive scores. A Violin plot showing immune reactive score in each MM (up) and patients were divided into high or low status group (bottom). B Bar chart showing the enrichment of specific pathways, based on the HALLMARK, GO-BP and KEGG gene sets of upregulated and downregulated genes in high-immune reactive status samples compared with low status samples. C Violin plots showing immune surveillance score and expressions of MHC class I molecules. D Violin plots showing immune escape score and expressions of immunosuppressive genes. Statistical analysis in A, C, D was performed by Wilcoxon test, ****p < 0.0001. High, n = 5; Low, n = 5

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Cell & Bioscience

ISSN: 2045-3701

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