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Fig. 1 | Cell & Bioscience

Fig. 1

From: Dynamic single-cell RNA-seq analysis reveals distinct tumor program associated with microenvironmental remodeling and drug sensitivity in multiple myeloma

Fig. 1

Single cell assessment revealed tumor heterogeneity in myeloma. A Schematic representation of the experimental strategy and sampling time-points of the study. B UMAP plot of single cells profiled in the presenting work colored by major cell types after fastMNN integration. C UMAP plot of single cells colored by plasma cell (PC) score according to expression of the plasma cell markers (SDC1/CD138, TNFRSF17 and SLAMF7). D UMAP plots showing the re-clustering of plasma cell (PC) colored by subclusters (left) and patients (right). E Pearson correlation matrix of averaged gene expression levels per patient. Top, cytogenetic information; bottom, averaged gene expression levels of five MM driver genes

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