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Fig. 9 | Cell & Bioscience

Fig. 9

From: Activation of goblet cell Piezo1 alleviates mucus barrier damage in mice exposed to WAS by inhibiting H3K9me3 modification

Fig. 9

Mechanical stimulation reduced the binding of H3K9me3 to mucin2 promoter through Piezo1. A–D Western blot and statistical analysis of Suv39h1, Hdac3, GAPDH, H3K9me3 and T-H3 in LS174T cells before and after UNC0638 intervention (n ≥ 5). E ELISA of mucin2 in LS174T cells after UNC0638 intervention (n ≥ 4). F ChIP-PCR test of H3k9me3 on the mucin2 promoter in LS174T cells under shear and shear stress plus 0.1 μm GsMTx4 (n ≥ 4)

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Cell & Bioscience

ISSN: 2045-3701

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