Fig. 6
From: Nrf2 is predominantly expressed in hippocampal neurons in a rat model of temporal lobe epilepsy
Nrf2 expression in neurons in the cortex and hippocampus at 1-week after SE. Representative fluorescent images of rat cortex (A), CA3 (C), and CA1 (E) regions of the hippocampus from sham animals and kainic acid induced-SE animals, illustrating colocalization of Nrf2 (red) with NeuN (green) and DAPI (blue). Scale bar = 50 µm (left panels) and 15 µm (right panels, zoomed view). B, D, F: The corresponding quantification of the number of cells double-positive for NeuN and Nrf2 in 1 mm2 of tissue, and normalized to the sham group. N = 5 rats/group. Results were expressed as mean ± SEM. **P < 0.01 compared to sham group by Mann–Whitney U test. B: p = 0.0556; D: p = 0.0079; F: p = 0.0079