Fig. 4
From: A synthetic pregnenolone analog promotes microtubule dynamics and neural development
P5 derivatives promote neurite extension and accelerate neuron development in vitro. A P5 and its derivatives increase neurite outgrowth in cerebellar granule neurons (CGNs) at DIV1. B Diverse effects of P5 and its derivatives on the length of axon-like processes in bipolar stage 3 of CGNs. One-way ANOVA with Dunnett’s post-hoc test was used for Panels A and B. C P5 and its derivative promote the development of GCNs at DIV 2. The numbers of unipolar stage 2 neurons and bipolar stage 3 neurons were quantified and represented as a percentage across treatments. Chi-square test is the statistical method used for this analysis