Fig. 6

Sevoflurane exposure down-regulating HCN2 in microglia and neurons in the hippocampus and cortex. A, Co-labeling of HCN2 with microglia or neurons in the hippocampus. Arrows indicate co-labeling of HCN2 with microglia or neurons. Microglia were labeled with iba1, and neurons were labeled with Neun. B, Co-labeling of HCN2 with microglia or neurons in the cortex. Arrows indicate co-labeling of HCN2 with microglia or neurons. C, The number of HCN2 co-labeled with microglia or neurons in the hippocampus (n = 4). D, The number of HCN2 co-labeled with microglia or neurons in the cortex (n = 4). Data are shown as mean ± SD. ^*P < 0.05 or ^**P < 0.01.