Fig. 5From: Hif-2α regulates lipid metabolism in alcoholic fatty liver disease through mitophagyModel describing the pivotal role played by Hif-2α in AFLD development. EtOH-exposed fatty liver tissue has higher levels of Hif-2α, which subsequently attenuate the expression of many target genes, including those directing mitophagy and fatty acid β-oxidation, thereby accelerating AFLD developmentBack to article page