Fig. 2

SS18/BAFs relocate from Pluripotent loci to somatic ones. A The combination analysis for the ATAC-seq, JUN ChIP-seq, SS18 ChIP-seq and BRG1 ChIP-seq, H3K27ac ChIP-seq data. All the ATAC-seq occupancy sites ± 5 kb of 0hs and 8 h were divided into five categories which were same with Fig. 1B. Number indicates peaks counts of each category. SE stands for TSS and TES, the following is the same. B Representative OC, CO, PON, POU, POD genomic views of multiple omics dataset including ATAC-seq, ChIP-seq and RNA-seq under BAFs/SS18 and JUN regulations during the process of JUN based PST and are marked in grey boxes. C ChIP-seq analysis for SS18 at 0 h during JUN based PST. Table list for the top10 most enrichment motifs. Peaks number = 5391. D ChIP-seq analysis for SS18 at 8 h during JUN based PST. Table list for the top10 most enrichment motif. Peaks number = 11,697. E Overlapped peaks for JUN and SS18 at 0 h and 8 h as indicated during JUN based PST indicated in venn plot. F Venn plot show changes in chromatin accessibility during the exit of pluripotency at the 0 and 8 h SS18 binding sites and at 8 h JUN binding sites