From: Host-dependent impairment of parasite development and reproduction in the acanthocephalan model
Gene | Log2 fold change | Adjusted p-value | Function |
---|---|---|---|
Aldolase 1* | 8.12 | 5.5E−11 | Developmental stage-specific or tissue -specific sugar-phosphate metabolisms |
Hexokinase A* | 6.63 | 3.6E−09 | Glucose homeostasis |
Glyceraldehyde 3 phosphate dehydrogenase 2 * | 5.47 | 2.4E−10 | Glucose homeostasis |
Phosphoglycerate kinase* | 5.25 | 8.6E−11 | Gluconeogenesis |
NUCB1 | 3.84 | 2.3E−17 | Carbohydrate metabolic process |
Pyruvate kinase* | 2.00 | 1.7E−17 | Muscle development, glycolysis and glucose homeostasis |
Glycogenin | 1.62 | 9.1E−07 | Glycogenin glucosyltransferase activity |
Glycerol-3-phosphate dehydrogenase 1 | 1.37 | 2.7E−05 | Enzymatic oxidation of glycerol-3-phosphate to dihydroxyacetone phosphate |
Glycogen phosphorylase | 1.29 | 2.3E−06 | Important allosteric enzyme in carbohydrate metabolism |
Trehalose-6-phosphate synthase 1 | 1.26 | 2.3E−04 | Enzymatic production of T6P using glucose-6-phosphate and UDP-glucose |
N-acetylglucosamine kinase | 1.20 | 3.6E-−04 | Carbohydrate phosphorylation |
Pyruvate carboxylase | 1.18 | 2.7E−05 | Gluconeogenesis |
Hexosaminidase 1 | 1.18 | 8.3E−05 | Protein deglycosylation and rhodopsin biosynthesis |
Poly(ADP-ribose) glycohydrolase | 1.16 | 9.1E−09 | Degrades poly(ADP-ribose) to mono(ADP-ribose) |
Glucosidase 2 α subunit | 1.15 | 9.3E−05 | Glucan 1,3-alpha-glucosidase activation; N-glycan processing |
Oscillin | 1.11 | 2.7E−05 | Glucosamine-6-phosphate deaminase activation |
Phosphoenolpyruvate carboxykinase 2* | 1.06 | 1.3E−03 | Manganese ion binding activation and phosphoenolpyruvate carboxykinase (GTP) activation |
4-alpha-glucanotransferase | 1.02 | 1.1E−09 | 4-alpha-glucanotransferase activation and amylo-alpha-1,6-glucosidase activation |
Malate dehydrogenase 1 | 1.01 | 3.7E−05 | Interconversion of malate and oxaloacetate |
Glycogen synthase | 1.01 | 1.3E−04 | Enzymatic linkage of glucose monomers into glycogen |