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Fig. 5 | Cell & Bioscience

Fig. 5

From: Integrating spatial transcriptomics with single-cell transcriptomics reveals a spatiotemporal gene landscape of the human developing kidney

Fig. 5

Spatial transcriptional network and heterogeneity of NPCs in the cortical regions of the a Correlations between module eigengenes and the spatial regions of the kidney. The numbers within the heatmap represent Pearson correlations and P-values (red, positively correlated; green, negatively correlated) of the module-region associations. The scale bar on the bottom indicates the Pearson correlation coefficient. R > 0.4 and a P-value < 10− 3 represent a strong correlation; b Gene ontology enrichment analysis reveals the biological function of differentially expressed genes in the M5 module related to kidney morphogenesis. c The connections among genes identified in the M5 module were constructed using online STRING analysis. The genes with an interaction score > 0.4 are shown in the network view. Pink color represents transcription factors, and blue indicates genes; d Spatial distribution of GDNF, ETV4, EYA1, CDK1, and FOXD1

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Cell & Bioscience

ISSN: 2045-3701

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