Fig. 1
From: Diabetes as a potential compounding factor in COVID-19-mediated male subfertility
![Fig. 1](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs13578-022-00766-x/MediaObjects/13578_2022_766_Fig1_HTML.png)
Direct infection of testicular cells by SARS-CoV-2. By binding to the highly expressed viral entry receptors on testicular cells, specifically the Sertoli cells, Leydig cells, and spermatogonia, SARS-CoV-2 may infect these cells and cause direct cell damage, metabolic reprogramming, and/or immune responses. The result would be cell dysfunction and apoptosis