Skip to main content
Fig. 5 | Cell & Bioscience

Fig. 5

From: The promoting effects of activated olfactory ensheathing cells on angiogenesis after spinal cord injury through the PI3K/Akt pathway

Fig. 5

Possible molecular mechanism of the pro-angiogenic effects of Activated OECs. a Growth factor array for angiogenic factors. Each bar shows the relative intensity ratios of growth factors found in activated OECs-CM, unactivated OEC-CM, or control media, respectively. b Western blotting detected protein levels of PI3K, p-PI3K, Akt, and p-Akt in each group. c and d represent the relative density of phosphorylation level of Akt and PI3K, respectively. e, f OECs-CM and MK2206 effect on migration of HUVECs using Transwell migration chambers. Scale bar: 100 μm. g, h OECs-CM and MK2206 effect on proliferation of HUVECs using EdU incorporation assay. ACM activated OECs-CM, UCM unactivated OECs-CM. All values shown are the means ± SD (n = 3). *P < 0.05, **P < 0.01, ***P < 0.005 vs the corresponding groups

Back to article page

Cell & Bioscience

ISSN: 2045-3701

Contact us