Fig. 6
From: The dual role of p62 in ferroptosis of glioblastoma according to p53 status
The clinical expression pattern and survival analysis of p62 in p53-wild-type and p53-mutant gliomas. A Difference analysis of ferroptosis enrichment score (ES) among different subtypes. According to the median value of p62, the level of ES were compared among low and high expression group in p53 mutant LGG, p53 wild-type LGG, p53 mutant GBM and p53 wild-type GBM. B Representatives of IHC staining of p62 and SLC7A11 expression in p53 mutant GBM and p53 wild-type GBM tissues. C Survival analysis of OS in four clusters in p62 (left) and NRF2 (right) respectively. Cluster 1: p53 mutant + p62 or NRF2 low expression, cluster 2: p53 mutant + p62 or NRF2 high expression, cluster 3: p53 wild-type + p62 or NRF2 low expression, cluster 4: p53 wild-type + p62 or NRF2 high expression