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Fig. 7 | Cell & Bioscience

Fig. 7

From: YTHDF1 promotes breast cancer progression by facilitating FOXM1 translation in an m6A-dependent manner

Fig. 7

The anti-tumor effect of YTHDF1 silence could be abrogated by FOXM1 overexpression. A Western blot analysis for FOXM1 and YTHDF1 in MDB-MA-231 and MCF-7 cells with sh-YTHDF1-2 (shYTH) or sh-YTHDF1#2 + pcDNA-FOXM1 plasmid (shYTH + FOXM1) B CCK-8 assay, C Transwell invasion assay, D wound healing assay and E Western blot assay for EMT-related proteins in MDB-MA-231 and MCF-7 cells with shNC, sh-YTHDF1#2 (shYTH) or sh-YTHDF1#2 + FOXM1 (shYTH + FOXM1). All data were presented as means ± SD of at least three independent repetitions. Values are significant at *P < 0.05, **P < 0.01, ***P < 0.001 as indicated

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