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Fig. 1 | Cell & Bioscience

Fig. 1

From: YTHDF1 promotes breast cancer progression by facilitating FOXM1 translation in an m6A-dependent manner

Fig. 1

YTHDF1 was highly expressed in breast cancer samples and cells. A YTHDF1 expression in breast cancer tissues and normal tissues from TCGA-BRCA dataset. Relative YTHDF1 mRNA expression in B collected breast cancer tissues and adjacent normal tissues samples, C MCF-10A and MCF-7 cells from GSE71862 dataset and D normal human breast cell line MCF-10A and breast cancer cell line MCF-7, MDA-MB-231, SKBR3, T47D and BT-549. Kaplan–Meier curves of OS in the TCGA dataset E and GSE29272 dataset F of all breast cancer patients with high and low YTHDF1 expression. G Immunohistochemical staining of YTHDF1 in a breast cancer sample. YTHDF1 protein expression in H breast cancer tissues and adjacent normal tissues and I normal human breast cell line MCF-10A and breast cancer cell line MCF-7, MDA-MB-231, SKBR3, T47D and BT-549. All data were presented as means ± SD of at least three independent repetitions. Values are significant at *P < 0.05, **P < 0.01, ***P < 0.001 as indicated

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