Fig. 5

In vivo TF administration during HFD prevents obesity establishment and WAT weight gains. Control mice (WT) were challenged to a high-fat diet (HFD) or standard diet (STD) for 2 weeks and subjected to TF (50 microg/Kg/day, i.p.) or vehicle (VH). Afterward, animals were fasted overnight, weighed, sacrificed and WAT depots (WAT) were dissected. A total body weight (BW) gain over the 2 weeks challenge and B epididymal (epiWAT), C subcutaneous (scWAT) D perirenal (prWAT) WAT depots weights normalized to BW N = 6–12. *p < 0.05 vs WT STD VH, #p < 0.05 vs WT HFD VH