Skip to main content
Fig. 3 | Cell & Bioscience

Fig. 3

From: Low-level laser prevents doxorubicin-induced skeletal muscle atrophy by modulating AMPK/SIRT1/PCG-1α-mediated mitochondrial function, apoptosis and up-regulation of pro-inflammatory responses

Fig. 3

Low level laser (LLL) exposure increases the phosphorylation of AMPK. C2C12 cells were exposed to various dosages of LLL for a total of 2 h. The expression levels of phosphorylated AMPK and total AMPK were investigated using Western blot assay (A). Protein expression levels were quantified and presented by a bar chart (B). C2C12 cells were treated with 2 µM doxorubicin (Dox) for 24 h, in the LLL-treated group, cells were exposed to LLL 8 J/m2 before Dox treatment. The expression level of phosphorylated AMPK and total AMPK were investigated using Western blot assay (C). Protein expression levels were quantified and presented by a bar chart (D). The data were presented as the mean ± SD of three biological replicates at three separate times. (* indicating p < 0.05 compared with the control group; #indicating p < 0.05 compared to Dox group)

Back to article page

Cell & Bioscience

ISSN: 2045-3701

Contact us