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Fig. 2 | Cell & Bioscience

Fig. 2

From: Low-level laser prevents doxorubicin-induced skeletal muscle atrophy by modulating AMPK/SIRT1/PCG-1α-mediated mitochondrial function, apoptosis and up-regulation of pro-inflammatory responses

Fig. 2

LLL exposure reverse Dox-induced muscle wasting in animals. The effects of LLL on Dox-induced muscle atrophy. The weight change (A), food intake (B), muscle mass (C), and cross-sectional area (D) in Con and Dox animals. Representative hematoxylin–eosin (H&E) and TUNEL stained soleus (E). The arrow heads indicated TUNEL ( brown color). Quantification of the percentage of TUNEL positive nuclei (F). Atrogin-1 (G) and MuRF-1 (H) mRNA expression levels in soleus muscle were investigated by real-time PCR. The data were presented as the mean ± SD of 8 animals. (* indicating p < 0.05 compared with the control group)

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Cell & Bioscience

ISSN: 2045-3701

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