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Table 2 Association of a polygenic risk score for LOY predisposition (LOY-PRS) as a continuous variable, with LOY measured in 5131 men

From: A polygenic risk score predicts mosaic loss of chromosome Y in circulating blood cells

 

OR (95% CI)*

p-value*

LOY-PRS

1.74 (1.62; 1.86)

 < 0.0001

Age, (years)

1.11 (1.09; 1.13)

 < 0.0001

Smoking

  

 Never/former

Reference

 

 Current

2.13 (1.53; 2.94)

 < 0.0001

Alcohol

  

 Never/former

Reference

 

 Current

1.21 (1.01; 1.47)

0.03

  1. * OR: odds ratios and p-values assessed using logistic regression
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Cell & Bioscience

ISSN: 2045-3701

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