From: A polygenic risk score predicts mosaic loss of chromosome Y in circulating blood cells
 | All (n = 5131) | LOY No (n = 3739) | LOY Yes (n = 1392) | p-value* |
---|---|---|---|---|
Age at Enrolment Mean (SD) | 74.9 (4.18) | 74.4 (3.84) | 76.3 (4.73) |  < 0.001 |
Smoking |  |  |  |  < 0.001 |
 Never | 2253 (43.9%) | 1680 (44.9%) | 573 (41.2%) | |
 Former | 2699 (52.6%) | 1952 (52.2%) | 747 (53.7%) | |
 Current | 179 (3.5%) | 107 (2.9%) | 72 (5.2%) | |
Alcohol | Â | Â | Â | 0.04 |
 Never | 461 (9.0%) | 359 (9.6%) | 102 (7.3%) | |
 Former | 294 (5.7%) | 211 (5.6%) | 83 (6.0%) | |
 Current | 4376 (85.3%) | 3169 (84.8%) | 1207 (86.7%) | |
Treatment | 0.57 | |||
 Placebo | 2564 (50.0%) | 1878 (50.2%) | 686 (49.3%) | |
 Aspirin | 2567 (50.0%) | 1861 (49.8%) | 706 (50.7%) | |
BMI (kg/m2) | Â | Â | Â | Â |
 Normal | 1063 (21.0%) | 754 (20.5%) | 309 (22.5%) | 0.07 |
 Underweight | 38 (0.8%) | 23 (0.6%) | 15 (1.1%) | |
 Overweight | 2633 (52.1%) | 1921 (52.2%) | 712 (51.9%) | |
 Obese | 1298 (25.7%) | 969 (26.3%) | 329 (24.0%) | |
 Missing | 18 (0.4%) | 12 (0.3%) | 6 (0.4%) |