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Table 1 Characteristics of the sample population

From: A polygenic risk score predicts mosaic loss of chromosome Y in circulating blood cells

 

All

(n = 5131)

LOY No

(n = 3739)

LOY Yes

(n = 1392)

p-value*

Age at Enrolment

Mean (SD)

74.9 (4.18)

74.4 (3.84)

76.3 (4.73)

 < 0.001

Smoking

   

 < 0.001

 Never

2253 (43.9%)

1680 (44.9%)

573 (41.2%)

 Former

2699 (52.6%)

1952 (52.2%)

747 (53.7%)

 Current

179 (3.5%)

107 (2.9%)

72 (5.2%)

Alcohol

   

0.04

 Never

461 (9.0%)

359 (9.6%)

102 (7.3%)

 Former

294 (5.7%)

211 (5.6%)

83 (6.0%)

 Current

4376 (85.3%)

3169 (84.8%)

1207 (86.7%)

Treatment

0.57

 Placebo

2564 (50.0%)

1878 (50.2%)

686 (49.3%)

 Aspirin

2567 (50.0%)

1861 (49.8%)

706 (50.7%)

BMI (kg/m2)

    

 Normal

1063 (21.0%)

754 (20.5%)

309 (22.5%)

0.07

 Underweight

38 (0.8%)

23 (0.6%)

15 (1.1%)

 Overweight

2633 (52.1%)

1921 (52.2%)

712 (51.9%)

 Obese

1298 (25.7%)

969 (26.3%)

329 (24.0%)

 Missing

18 (0.4%)

12 (0.3%)

6 (0.4%)

  1. * Using the LOY binary variable, t-test or chi-square test we performed for continuous and categorical variables, respectively