Fig. 1From: Single-cell RNA-sequencing reveals distinct immune cell subsets and signaling pathways in IgA nephropathySingle-cell landscape of peripheral blood mononuclear cells (PBMCs) from healthy control donors and IgAN patients. A Schematic flowchart of scRNA-seq experimental design of this study. Control (CTRL) n = 6; IgAN n = 10. B, C UMAP illustration of integrated scRNA-seq data from CTRL and IgAN colored by cell-type annotation (B) and cells of origin (C). D Heatmap of top ten marker genes of each cell cluster. E Stacked bar graphs of the cell-type composition in PBMCs from CTRL and IgAN. F Bar graphs of each cell cluster population between CTRL and IgAN. CTRL n = 6; IgAN n = 10; Mean ± SEM; *p < 0.05Back to article page