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Fig. 6 | Cell & Bioscience

Fig. 6

From: Neuromedin B promotes chondrocyte differentiation of mesenchymal stromal cells via calcineurin and calcium signaling

Fig. 6

Role of NMB in calcium signaling. A Time course of maximal calcium intensity of spontaneous calcium oscillations in BM-MSCs transfected with siCT or siNMB and loaded with Fluo-4-AM at day 3 of chondrogenesis. B Calcium responsive rate determined in BM-MSCs transfected with siCT or siNMB at day 3 of chondrogenesis and expressed as fold change rate. C Intracellular calcineurin phosphatase activity determined in BM-MSCs transfected with siCT or siNMB at day 3 of chondrogenesis. D Fold change expression of SOX9 in BM-MSCs transfected with siCT or siNMB at day 3 of chondrogenesis. *: p ≤ 0.05, **: p ≤ 0.01

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