Fig. 3From: Metabolic reprogramming and metabolic sensors in KSHV-induced cancers and KSHV infectionKSHV enhances lipogenesis and peroxisome-mediated ß-oxidation of lipids. The acetyl-CoA from KSHV-enhanced glycolysis leads to upregulated fatty acids synthesis; the ß-oxidation of lipids in peroxisomes is enhanced by short-term KSHV infection; and KSHV enhances the phosphorylation of sphingolipid sphingosine by upregulating the SphK1Back to article page