Fig. 4
From: A novel mechanism for C1GALT1 in the regulation of gastric cancer progression
Effects of C1GALT1 on GC proliferation, migration, and invasion are mediated by integrin α5. a–c Cell proliferation, migration, and invasion were assessed by CCK-8, Transwell migration, and Matrigel invasion assays. d Photographs of xenograft tumors. e The tumor growth curve and tumor weight in the nude mice. f Metastatic nodules were photographed and counted. n = 6 mice per group. Mock: cells transfected with empty plasmid; OV: cells transfected with C1GALT1 plasmid; siNC: cells transfected with negative control siRNA; siRNA: cells transfected with integrin α5 siRNA. *p < 0.05, **p < 0.01 compared with the siNC+Mock group (Student’s t-test or one-way ANOVA)