Parameter | Non drinker | ALD | Non-pathological alcohol drinker controls | ||||
---|---|---|---|---|---|---|---|
Healthy control | Alcoholic fatty liver disease | Alcoholic cirrhosis | Mixed cirrhosis | Binge drinker | HDC | HBV liver cirrhosis | |
Number | 116 | 4 | 48 | 33 | 34 | 11 | 7 |
Alcohol withdrawal (> 1 year) | – | 0 | 23 | 33 | – | – | – |
Excessive drinks in the last 30d | – | – | 10 | 0 | 34 | 11 | – |
Gender Male (%) | 93(80.2%) | 3(75%) | 47(97.9%) | 33(100%) | 19(55.9%) | 11(100%) | 7(100%) |
Age(year) | 48.89 ± 11.21 | 40.25 ± 3.30* | 53.6 ± 15.62 | 52.21 ± 6.30 | 28.34 ± 9.59** | 51.36 ± 10.62 | 51.86 ± 3.18 |
ALT(U/L) | 26.3 ± 30.54 | 71 ± 28.57 | 40.4 ± 52.42 | 32.25 ± 17.73 | 24.4 ± 5.77 | 51.73 ± 89.31 | 28.71 ± 16.04 |
AST(U/L) | 21.08 ± 11.43 | 49 ± 15.28 | 59.29 ± 64.85** | 39.88 ± 19.14** | 23.6 ± 5.18 | 24 ± 10.68 | 24.43 ± 9.03 |
TBIL (μmol/L) | 13.76 ± 5.89 | 21.63 ± 15.26 | 44.34 ± 49.55** | 21.54 ± 19.63 | 8.94 ± 4.68 | 16.56 ± 14.56 | 19.24 ± 7.79 |
ALB(g/L) | 41.75 ± 3.38 | 37.08 ± 9.40 | 31.63 ± 4.86** | 32.76 ± 6.45** | 46.82 ± 4.03 | 39.24 ± 4.98 | 39 ± 1.53 |
ALP(U/L) | 78.10 ± 20.21 | 86.25 ± 13.57 | 140.16 ± 54.89** | 124.63 ± 49.86** | 66.75 ± 15.59 | 78.73 ± 17.64 | 83.14 ± 13.06 |
GGT(U/L) | 31.71 ± 47.43 | 143.75 ± 108.69 | 149.78 ± 170.36** | 70.16 ± 59.74* | 23.75 ± 10.99 | 49.64 ± 58.96 | 26.14 ± 24.65 |
PT(s) | 11.70 ± 1.02 | 13.1 ± 0.95 | 15.80 ± 3.21 | 15.39 ± 3.16 | – | 11.95 ± 0.7 | 12.13 ± 0.8 |
WBC (× 109/L) | 5.8 ± 1.59 | 7.87 ± 2.42 | 4.83 ± 2.22 | 4.0 ± 4.04 | 9.8 ± 3.64** | 6.1 ± 0.73 | 4.99 ± 0.77 |
NEUT (%) | 54.59 ± 7.57 | 71.45 ± 10.58 | 61.37 ± 15.98 | 58.73 ± 11.27 | 71.37 ± 12.45** | 58.6 ± 8.64 | 53.03 ± 7.4 |
Neutrophil (× 109/L) | 3.22 ± 1.21 | 5.75 ± 2.56 | 3.05 ± 1.91 | 2.47 ± 2.98 | 7.22 ± 3.52** | 3.63 ± 0.86 | 2.94 ± 1.2 |
Lymphocyte (× 109/L) | 2.37 ± 4.39 | 1.44 ± 0.51 | 1.18 ± 0.85 | 0.92 ± 0.81* | 2.11 ± 0.99 | 1.87 ± 0.41 | 1.85 ± 0.39 |