Fig. 3

PARP11 suppresses ZIKV independent on the regulation of IFNAR1 protein level. a Western blotting analysis of lysates from A549 cells infected with VSV, ZIKV and mock control. b Densitometry analysis of the data in (a). c Western blotting analysis of lysates from WT and PARP11^−/− A549 cells infected with VSV, ZIKV and mock control. d Densitometry analysis of the data in (c). e Western blotting analysis of lysates from WT and PARP11^−/− A549 cells infected with ZIKV and mock control. f Densitometry analysis of the data in (e). Densitometry analysis data (b, d and f) are mean ± SEM pooled from three independent experiments. Western blotting results (a, c and e) are presentative of three independent experiments. ns, not significant, **P < 0.01, and ***P < 0.001 by Student’s t test