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Fig. 6 | Cell & Bioscience

Fig. 6

From: Cell subtypes and immune dysfunction in peritoneal fluid of endometriosis revealed by single-cell RNA-sequencing

Fig. 6

Dysfunction of NK cells in endometriosis. a Enriched KEGG pathway of natural killer cell mediated cytotoxicity of cluster 8. Red presents differentially expressed gene. b Enriched GO terms of natural killer cells. c Gene Set Enrichment Analysis of positive regulation of natural killer cell mediated cytotoxicity pathway and positive regulation of lymphocyte chemotaxis pathway of natural killer cells in endometriosis and control samples. d Mean gene expressions of GNLY, GZMB, GZMH, CCL3 and XCL1 of natural killer cells in endometriosis and control samples. e mRNA expressions of GZMB and XCL1 of primary NK cells in peritoneal fluid were detected by Quantitative PCR analysis for the endometriosis group (n = 9) and control group (n = 9). Data in Fig. 6d and Fig. 6e are presented as mean ± SEM. EMs endometriosis, NES normalized enrichment score, FDR false discovery rate

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Cell & Bioscience

ISSN: 2045-3701

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