Urine-derived induced pluripotent/neural stem cells for modeling neurological diseases

Cell & Bioscience

Table 1 The expression of cell surface markers in USCs

Surface markers in USCs		% of expression	References
Embryonic stem cell markers	TRA-1–81	±	[42]
	TRA-1–60	±	[42]
	SSEA4	+	[42]
Epithelial markers	E-cadherin	+	[32, 52]
	β-catenin	+	[32, 52]
	Occludin	+	[32]
	Claudin 1	+	[32]
	ZO-1	+	[32, 52]
	KRT7	+	[8, 32, 52]
	KRT14	+	[53]
	KRT15	+	[53]
	KRT16	+	[53]
	KRT18	+ (type I),—(type II)	[41]
	KRT19	+	[53]
	CD326	+	[53]
Epithelial basal markers	CD44	+	[25, 38, 54]
Renal epithelial markers	CD13	+	[23, 32, 44, 52]
	L1CAM	+	[52]
	NR3C2	+
	SLC2A1	+
	CD24	+	[41]
	CD29	+
	CD34	−
	CD73	+
	CD90	+
	CD105	+
	CD133	±
	UMOD	+ (type I),—(type II)
	NPHS1	+ (type I),—(type II)
	AQP1	+ (type I),—(type II)
	AQP2	−
	SLC12A1	+ (type I),—(type II)
Mesenchymal stem cells markers	SSEA-4	+	[25, 55]
	CD29	+	[38, 44]
	CD73	+	[25, 31, 38, 55]
	CD90	+	[31, 38, 44]
	CD105	±	[25, 31, 38, 44]
	CD166	+	[44]
	STRO-1	+	[25]
Fibroblast markers	Actin	+	[32, 52]
	Vimentin	±	[32, 52]
	Fibronectin	±	[32, 52]
	Twist 1	−	[32]
	Slug	−	[32]
Pericyte markers	CD146	± , +	[25, 31, 42]
	NG2	±	[25, 42]
	PDGF-rβ (CD 140b)	±	[25, 42]
Hematopoietic stem cells markers	CD11b	−	[42, 56]
	CD14	−	[56]
	CD31	−	[25]
	CD34	−	[25, 31, 38, 44]
	CD45	-, ±	[25, 31, 44, 54]
	CD133	±	[25, 38]
	CD309	−	[38]
	HLA-ABC (MHC-1)	+	[42, 57]
	HLA-DR (MHC-II)	−	[38, 42, 44, 51]

−: percentage of expression < 1%, ± : 1% < percentage of expression < 50%, + : percentage of expression > 50%

ISSN: 2045-3701