Fig. 8From: EIF5A2 controls ovarian tumor growth and metastasis by promoting epithelial to mesenchymal transition via the TGFβ pathwayKnockout of EIF5A2 using lentiviral CRISPR/Cas9 nickase vector suppressed ovarian tumor metastasis in an orthotopic ovarian mouse model. a Metastatic tumors in liver and spleen of mice xenografted with EIF5A2 KO and control (Con) cells. b Sections of metastatic tumors in liver and spleen were stained with H&E. Arrow indicates tumor areaBack to article page