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Fig. 2 | Cell & Bioscience

Fig. 2

From: EIF5A2 controls ovarian tumor growth and metastasis by promoting epithelial to mesenchymal transition via the TGFβ pathway

Fig. 2

Disruption of EIF5A2 expression using lentiviral CRISPR/Cas9 nickase mediated editing resulted in the inhibition of EMT in ovarian cancer cells. a Western blot analysis of EIF5A2 and EMT markers in EIF5A2 KO and control (Con) SKOV3 and OVCAR8 cells. b Western blot analysis of EIF5A2 and EMT markers in EIF5A2 expression and control OVCAR3 cells. Band intensity was measured using Image J and statistically analyzed. One representative western blot was presented from three similar independent experiments. (*p < 0.05, **p < 0.01,*** p < 0.001)

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