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Table 1 The summary of cellular localization of SARS-CoV-2 proteins

From: Characterization of SARS-CoV-2 proteins reveals Orf6 pathogenicity, subcellular localization, host interactions and attenuation by Selinexor

SARS-CoV-2 Protein Confirmed subcellular localization by confocal microscopy
Nsp1 cytosol, perinuclear region
Nsp2 cytosol
Nsp3 membrane of vesicles, plasma membrane, not ER
Nsp6 ER, perinuclear region
Orf3a Golgi, weakly at ER, plasma membrane, lumen of vesicles
Orf3b cytosol, lumen of vesicles
Orf6 ER, membrane of vesicles (autophagosome, lysosome)
Orf7a mostly at Golgi, weekly at ER and mitochondria
Orf7b ER
Orf8 ER
Orf9b cytosol, plasma membrane
Orf10 cytosol, plasma membrane, perinuclear region