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Table 2 The relationship between NEAT1 expression in serum EVs and clinical characteristics of BC patients [n (%)]

From: Long non‐coding RNA NEAT1 transported by extracellular vesicles contributes to breast cancer development by sponging microRNA-141-3p and regulating KLF12

Clinical data Cases NEAT1 expression in serum EVs P
Low (n = 34) High (n = 28)
Age     0.317
 < 50 years 29 18 (62.1) 11 (37.9)  
 ≥ 50 years 33 16 (48.5) 17 (51.5)  
Tumor diameter     0.127
 ≤ 2 cm 27 18 (66.7) 9 (33.3)  
 > 2 cm 35 16 (45.7) 19 (54.3)  
Clinical stages     0.123
 I + II 36 23 (63.9) 13 (36.1)  
 III + IV 26 11 (42.3) 15 (57.7)  
Lymph node metastasis     0.03
 Yes 41 18 (43.9) 23 (56.1)  
 No 21 16 (76.2) 5 (23.8)  
PR expression     0.001
 Positive 39 15 (38.5) 24 (61.5)  
 Negative 23 19 (82.6) 4 (17.4)  
ER expression     0.010
 Positive 35 14 (40.0) 21 (60.0)  
 Negative 27 20 (74.1) 7 (25.9)  
Ki-67 expression     0.004
 Positive 38 15 (39.5) 23 (60.5)  
 Negative 24 19 (79.2) 5 (20.8)  
  1. NEAT1 Nuclear paraspeckle assembly transcript 1, BC breast cancer, EVs extracellular vesicles, PR progesterone receptor, ER estrogen receptor