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Table 2 The relationship between NEAT1 expression in serum EVs and clinical characteristics of BC patients [n (%)]

From: Long non‐coding RNA NEAT1 transported by extracellular vesicles contributes to breast cancer development by sponging microRNA-141-3p and regulating KLF12

Clinical data

Cases

NEAT1 expression in serum EVs

P

Low (n = 34)

High (n = 28)

Age

   

0.317

 < 50 years

29

18 (62.1)

11 (37.9)

 

 ≥ 50 years

33

16 (48.5)

17 (51.5)

 

Tumor diameter

   

0.127

 ≤ 2 cm

27

18 (66.7)

9 (33.3)

 

 > 2 cm

35

16 (45.7)

19 (54.3)

 

Clinical stages

   

0.123

 I + II

36

23 (63.9)

13 (36.1)

 

 III + IV

26

11 (42.3)

15 (57.7)

 

Lymph node metastasis

   

0.03

 Yes

41

18 (43.9)

23 (56.1)

 

 No

21

16 (76.2)

5 (23.8)

 

PR expression

   

0.001

 Positive

39

15 (38.5)

24 (61.5)

 

 Negative

23

19 (82.6)

4 (17.4)

 

ER expression

   

0.010

 Positive

35

14 (40.0)

21 (60.0)

 

 Negative

27

20 (74.1)

7 (25.9)

 

Ki-67 expression

   

0.004

 Positive

38

15 (39.5)

23 (60.5)

 

 Negative

24

19 (79.2)

5 (20.8)

 
  1. NEAT1 Nuclear paraspeckle assembly transcript 1, BC breast cancer, EVs extracellular vesicles, PR progesterone receptor, ER estrogen receptor
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Cell & Bioscience

ISSN: 2045-3701

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