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Table 4 Univariate and multivariate analyses of the recurrence-free survival in 135 HCC cases

From: DNA primase subunit 1 deteriorated progression of hepatocellular carcinoma by activating AKT/mTOR signaling and UBE2C-mediated P53 ubiquitination

Parameters

Univariate analysis

Multivariate analysis

HR

95% CI

P

HR

95% CI

P

PRIM1 expression

High vs. low

3.283

2.083–5.173

< 0.001

1.733

1.038–2.893

0.036

Age (years)

 < 60 vs. ≥ 60

0.857

0.520–1.414

0.545

   

Sex

 Male vs. female

1.026

0.579–1.819

0.930

   

AFP level

 Positive vs. negative

1.520

0.894–2.586

0.119

   

Tumor size (cm)

 < 3 vs. ≥ 3

3.311

1.654–6.627

< 0.001

1.849

0.873–3.915

0.108

Edmondson-Steiner grade

 I + II vs. III + IV

2.172

1.048–4.503

0.032

1.878

0.882–3.997

0.102

Ascites

 Absent vs. present

2.405

1.541–3.754

< 0.001

2.431

1.516–3.898

< 0.001

 TNM stage

I + II vs. III + IV

3.024

1.903–4.805

< 0.001

2.201

1.306–3.707

0.003

  1. PRIM1 DNA primase subunit 1, TNM tumor-node-metastasis
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Cell & Bioscience

ISSN: 2045-3701

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