Table 1 Differences between M1 and M2 macrophages
From: Mechanism of mesenchymal stem cells in spinal cord injury repair through macrophage polarization
Types | Inducing factor | Molecular marker | Characteristic cytokine |
|---|---|---|---|
M1 macrophages | TH1 cytokines (such as IFN-γ, lipopolysaccharide, TNF-α) | iNOS, CD16/32, CD80, CD86, MHC II | IL-1β, IL-12, IL-6, IL-23, TNF-α, IFN-γ |
M2 macrophages | TH2 cytokines (such as IL-4, IL-10, IL-13) | CD206, CD163, Arg1, Fizz1, YM1 | IL-4, IL-10, IL-13, TGF-β |