Fig. 5

BTX-A inhibited IKKα/β activation and phosphorylation of SNAP23 via restraining TLR2/MyD88 signaling. a Expression of p-IKKα/β in microglias transfected with pcDNA-TLR2 or pcDNA-MyD88 following LPS and BTX-A was measured by western blotting assay. b Expression levels of p-IKKα/β and p-SNAP23 in microglias transfected with pcDNA-TAK1 following LPS and BTX were determined using western blotting assay. **P < 0.01 contrasted with Ctrl group, ^##P < 0.01 contrasted with LPS group, and ^$$P < 0.01 compared with LPS + BTX-A group