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Table 1 Distribution of KLHL18 status in non-small cell lung cancer according to clinicopathological characteristics

From: KLHL18 inhibits the proliferation, migration, and invasion of non-small cell lung cancer by inhibiting PI3K/PD-L1 axis activity

Characteristics Number of patients KLHL18 overexpression KLHL18 negative or weak expression P-value
Age
 ≥ 50 years 139 79 (56.83%) 60 (43.17%) 0.245
 < 50 years 75 49 (65.33%) 26 (34.67%)  
Sex
 Male 110 65 (59.10%) 45 (40.90%) 0.889
 Female 104 63 (60.58%) 41 (39.42%)  
Histology
 Adenocarcinoma 113 68 (60.18%) 45 (39.82%) 1.000
 Squamous cell carcinoma 101 60 (59.41%) 41 (40.59%)  
TNM stage
 I–II 138 91 (65.94%) 47 (34.06%) 0.019
 III 76 37 (48.68%) 39 (51.32%)  
Nodal status
 N0 137 98 (71.53%) 39 (28.47%)  < 0.0001
 N1, N2, N3 77 30 (38.96%) 47 (61.04%)  
Differentiation
 Well-moderate 118 68 (57.63%) 50 (42.37%) 0.487
 Poor 96 60 (62.50%) 36 (37.50%)  
Tumor size
 ≥ 3 cm 126 68 (53.97%) 58 (46.03%) 0.037
 < 3 cm 88 60 (68.18%) 28 (31.82%)