Fig. 2

MSCs alleviate docetaxel-induced CRPC cells proliferation decrease and apoptosis increase in vivo. a Real-time PCR was employed to examine the PCNA expression level of tumors. Results were reported as ratio to control group. Real-time PCR was employed to examine the Caspase-3 expression level of tumors. Results were reported as ratio to control group. b Tumor tissues were analyzed for immunohistochemical staining of Ki-67. Apoptosis of 4T1 tumor tissues were determined by TUNEL assay. c Typical photographs were presented (original magnification ×200). The quantification of Ki-67-positive cells per HP and TUNEL-positive tumor cells was shown as mean ± SD. *P < 0.05; **P < 0.01