Skip to main content
Fig. 5 | Cell & Bioscience

Fig. 5

From: Efficacy of a novel double-controlled oncolytic adenovirus driven by the Ki67 core promoter and armed with IL-15 against glioblastoma cells

Fig. 5

Tube formation capacity of HUVECs incubated in different U251 conditioned media. a Glioma cells U251 were respectively treated with Ad5-GFP, Ad5-Ki67/GFP, Ad5-Ki67/IL15 (MOI = 40) for 72 h, and at which time different U251 conditioned media (Ad5-GFP-CM, Ad5-Ki67/GFP-CM and Ad5-Ki67/IL15-CM) were collected. Angiogenic capacity of HUVECs cultured by CM, Ad5-GFP-CM, Ad5-Ki67/GFP-CM and Ad5-Ki67/IL15-CM (MOI = 40) for 6 h on Matrigel (×100, scale bars = 500 µm). CM represented the untreated U251 conditioned medium. b, c Total segments length and quantification of number of tubes generated by HUVECs incubated with different conditioned media. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001

Back to article page

Cell & Bioscience

ISSN: 2045-3701

Contact us